Blood pressure increases with age and as the world's population ages, the number of hypertensive and prehypertensive individuals is soaring.
- In the United States, one in three adults, or 65 million Americans, suffer from hypertension and another 59 million are considered prehypertensive.1
- According to the World Health Organization (WHO), 600 million people worldwide suffer from blood pressure, with 7.1 million dealths annually caused by hypertension.2
The Ocean Nutrition Solution
Levenorm™ is a patented natural ingredient that supports healthy blood pressure level in prehypertensive people.
Description
Levenorm™ is a fish protein hydrolysate from Bonito Tuna species comprised of eight active oligopeptides.
Mode of Action
Inhibition of Angiotensin Converting Enzyme (ACE)
Product Attributes
- Inhibits ACE to reduce total peripheral resistance of the vasculature.
- Supports healthy blood pressure levels when elevated beyond the normal range.
- Does not affect blood pressure in healthy, normotensive individuals.
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Features |
Benefits |
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Supports the management of healthy blood pressure levels in prehypertensive individuals3,4,5 |
Growing consumer demand – addresses the unmet need of the huge prehypertensive market |
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Clinically proven |
Efficacy & safety confirmed; increased consumer confidence |
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Low dosage: 1.5g/day |
Facilitates consumer compliance resulting in repeat sales |
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Patent protected ingredient |
Protects your marketing investment |
Levenorm™, Supported with Science & Research
Efficacy proven in three major human intervention (Phase II) clinical trials involving over 130 subjects.
- Average drop of 10.2 mmHg in systolic blood pressure (SBP) and 7 mmHg in diastolic blood pressure (DBP) at a dose of 1.5g/day.4
- No side effects reported.3,4,5
Fifty percent inhibitory concentration (IC50) is approximately 33 mg/ml, the strongest commercially available natural ACE-inhibitor.
- Proven safe: no toxic effects observed in animal and cell toxicity studies, or human trials.3,4,5
References:1 American Heart Association, Heart Disease and Stroke Statistics - 2006 Update, pg. 18.
2 American Heart Association, International Cardiovascular Disease Statistics, 2004.
3 Data on file.
4 Nutrition Research.2001; 21:1149-58.
5 Immunopharmacology.1999;44:123-7.
